CD103 Antigen

The CD103 antigen was originally described as the human mucosal antigen 1 (HML-1) and was subsequently proved to be the integrin αE subunit. CD103 is composed of a 150 kDa chain associated with a 25 kDa chain by a disulfide bond. It is expressed as a heterodimer in association with the integrin β7 chain. CD103 is expressed on mucosa-associated T lymphocytes and activated cells. This human intra-epithelial lymphocyte marker is expressed in very few resting peripheral blood lymphocytes. αEβ7 binds to E-cadherin on epithelial cells. Activation and TGFβ-1 induce CD103 expression.


 Clone: 2G5  Isotype: IgG2a Mouse

The 2G5 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes.
 

Choose a CD103 Model

Product Line Specifications

Format Liquid
Specificity CD103
Form APC
Clone 2G5
Isotype IgG2a Mouse
Cross Reactivity Indian Rhesus, Sooty Mangabey
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B06204

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


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